At present, many want to have children of infertility patients, elderly women choose to do IVF to get to sustain life, but in front of IVF embryos implanted in a womb, how to exclude embryonic born with genetic diseases and hazards healthy babies, patients and the medical profession has become a common concern. Not long ago, Chinese PLA General Hospital, Professor Yao Yuanqing led research team has successfully developed a new generation of single cell based on previous whole-genome sequencing embryo implantation genetic testing technology, than the traditional method goes a step further.

According to reports, the technology can be combined with family-related genetic information, once for all chromosome copy number detection, to more accurately distinguish abnormal structure 1Mb size. Compared with the past, the traditional technology, this technology platform even more rapid, accurate, and less expensive, with a wide range of clinical applications. 2012 "China infertility Investigation" Data show that China's incidence of infertility accounts for about 15% -20% of women of reproductive age. "In clinical practice, whether natural conception or IVF Cycles, senior citizens (35 and older) women are significantly lower chance of conceiving." Many patients need the help of IVF-assisted breeding, deputy director of the PLA General Hospital Wang Hui, MD. "As women age, the incidence of embryonic chromosomal abnormalities increased year by year over the age of embryonic chromosomal abnormalities .35 ratio as high as 60% -80%, about 50% of the embryos are aneuploid chromosome abnormalities." Said Wang Hui Therefore, before the embryo implanted in a womb, the embryo to detect abnormal chromosome number and structure, high-quality selection of chromosomally normal embryos for transplantation, improving infertility patient "test-tube baby 'pregnancy rates, lower abortion rates and birth defects key.

Wang Hui, at present, preimplantation genetic testing technology mainly includes two aspects: one is pre-implantation genetic screening (PGS), chromosome genetic screening for couples at high risk of infertility, to exclude aneuploid embryos; the other is preimplantation genetic diagnosis (PGD), infertility patients for specific genetic diseases (monogenic disease, abnormal chromosome structure, etc.), one-time its 24 chromosomes testing, which excludes with hereditary diseases and their risk of fertilized embryos, preferably a healthy embryo, and then transplanted into the uterus of normal bred through artificial means. Not only can the treatment of infertility, can also block the spread of genetic diseases, reduce human genetic load. "Clinical pregnancy human assisted reproductive technology for years hovered at around 40 percent, both in 2013 based on randomized controlled trials of whole genome detection PGS small sample showed, PGS clinical pregnancy rate can be increased to 75%. This a data suggest that genetic testing of embryos before implantation technique could be to improve the pregnancy rate of assisted reproductive technology breakthrough. "Yao Yuanqing said.